High resolution views of a receptor molecule that is implicated in cancer offer a clear target for the development of a new class of cancer drugs, Yale School of Medicine researchers report July 27 in Cell. It is also anticipated that the new family of drugs may be applied for the treatment of gastrointestinal stromal tumor (GIST) cancers that are resistant to Gleevec and Sutent. Although these drugs would target the same receptors as Gleevec and Sutent, they would do so by a different mechanis Join discussion...

A new targeted drug delivery method uses ultrasound to image tumors, while also releasing the drug from "nanobubbles" into the tumor. Cancer drugs can be targeted to tumors by delivering them in packets of nanoparticles, then releasing them with ultrasound. But this approach can be difficult because it requires a way to image the tumor prior to treatment. Natalya Rapoport, Ph.D., D.Sc., of the University of Utah in Salt Lake City and colleagues describe a new method of drug delivery that may a Join discussion...