Fear of inability to get insurance or withdrawel of insurance keeps people from getting DNA testing Join discussion...

The long-term cancer risk of mobile phone use cannot be ruled out, experts have concluded. A major six-year research programme found a "hint" of a higher cancer risk. Join discussion...

Bilateral orchiectomy or luteinizing hormone–releasing hormone agonists are recommended initial androgen-deprivation treatments (ADTs). Nonsteroidal antiandrogen monotherapy merits discussion as an alternative; steroidal antiandrogen monotherapy should not be offered. Combined androgen blockade should be considered. In metastatic or progressive PCa, immediate versus symptom-onset institution of ADT results in a moderate decrease (17%) in relative risk (RR) for PCa-specific mortality, a moderate increase (15%) in RR for non–PCa-specific mortality, and no overall survival advantage. Therefore, the Panel cannot make a strong recommendation for early ADT initiation. Prostate-specific antigen (PSA) kinetics and other metrics allow identification of populations at high risk for PCa-specific and overall mortality. Further studies must be completed to assess whether patients with adverse prognostic factors gain a survival advantage from immediate ADT. For patients electing to wait until symptoms for ADT, regular monitoring visits are indicated. For patients with recurrence, clinical trials should be considered if available. Currently, data are insufficient to support use of intermittent androgen blockade outside clinical trials. Join discussion...

Guidelines for the management of gastroenteropancreatic neuroendocrine tumours Join discussion...

Neuroendocrine Tumors NCCN Clinical Practice Guidelines Join discussion...

By the American Urological Association Join discussion...

To update the recommendations for the use of bisphosphonates in the prevention and treatment of bone disease in multiple myeloma. The Update Committee expanded the guideline to include a discussion of osteonecrosis of the jaw (ONJ). Join discussion...

Kidney Cancer - NCCN Clinical Practice Guidelines in Oncology Join discussion...

Collaborating scientists in Boston and North Carolina have found that a particular gene can block key steps of the lung cancer process in mice. The researchers report in the journal Nature that LKB1 is not only a "tumor-suppressor" gene for non-small cell lung cancer in mice, it also may be more powerful than other, better-known suppressors. The study will be published on the journal's Web site on Aug. 5 and later in a print version. If further research shows LKB1 has a similar effect in human Join discussion...

Mobile phones and cancer Join discussion...